Interventions for infantile esotropia

S Elliott1, A Shafiq

  • 1Ophthalmology Department, Salisbury Health Care NHS Trust, Salisbury District Hospital, Salisbury, Wiltshire, UK, SP2 8BJ. sue.elliott@salisbury.nhs.uk

Insights

This review found no studies on infantile esotropia interventions, highlighting a critical need for high-quality trials. Current evidence is insufficient to guide treatment decisions for this condition.

Area of Science:

  • Ophthalmology
  • Pediatric Ophthalmology
  • Strabismus Management

Background:

  • Clinical management of infantile esotropia (IE) lacks clarity regarding optimal interventions and timing.
  • Uncertainty exists on the most effective surgical and non-surgical treatment approaches for IE.
  • The ideal age for initiating treatment for infantile esotropia remains a significant question.

Purpose of the Study:

  • To evaluate the efficacy of diverse surgical and non-surgical interventions for infantile esotropia.
  • To determine the impact of treatment age on outcomes in infantile esotropia management.
  • To synthesize existing evidence on infantile esotropia treatment effectiveness.

Main Methods:

  • Systematic review of randomized controlled trials (RCTs) for infantile esotropia interventions.
  • Comprehensive literature search including Cochrane CENTRAL, MEDLINE, EMBASE, LILACS, and conference proceedings.
  • Manual searches and direct contact with researchers to identify all relevant published and unpublished studies.

Main Results:

  • No randomized controlled trials met the selection criteria for this review.
  • The review could not identify any studies suitable for analysis regarding infantile esotropia interventions.
  • Consequently, no data was available to assess the effectiveness of different treatments or the significance of intervention age.

Conclusions:

  • Existing literature on infantile esotropia interventions primarily consists of retrospective and prospective cohort studies.
  • This review could not resolve controversies surrounding the type of surgery, non-surgical options, or optimal age for intervention in IE.
  • There is an urgent need for high-quality randomized trials to establish a robust evidence base for managing infantile esotropia.
Abstract

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