Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cardiac tissue ablation with catheter-based microwave heating.

C Rappaport1

  • 1Department of Electrical and Computer Engineering, Northeastern University, Boston, MA 02115, USA. rappaport@neu.edu

International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
|January 29, 2005
PubMed
Summary

Microwave Cardiac Ablation (MCA) offers a minimally invasive surgical alternative for treating atrial fibrillation by precisely heating cardiac tissue. This novel antenna design creates wider, deeper lesions than traditional RF ablation.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical Practice Guideline for the prevention and early detection of breast and ovarian cancer in women from HBOC (hereditary breast and ovarian cancer) families.

Wiener klinische Wochenschrift·2015
Same author

Clinical implications of genetic testing for BRCA1 and BRCA2 mutations in Austria.

Clinical genetics·2013
Same author

Presence of intratumoral stem cells in breast cancer patients with or without BRCA germline mutations.

Current cancer drug targets·2011
Same author

New perfluorocarbon system for multilayer growth of anchorage-dependent mammalian cells.

BioTechniques·2002
Same author

Monte Carlo simulations of electromagnetic wave scattering from a random rough surface with three-dimensional penetrable buried object: mine detection application using the steepest-descent fast multipole method.

Journal of the Optical Society of America. A, Optics, image science, and vision·2002
Same author

Novel oxygenation system supports multilayer growth of HeLa cells.

BioTechniques·1996

Area of Science:

  • Cardiology
  • Biomedical Engineering
  • Minimally Invasive Surgery

Background:

  • Atrial fibrillation is commonly treated by surgically removing diseased cardiac tissue.
  • Existing treatments like Radio Frequency (RF) ablation have limitations in precise tissue heating.
  • Microwave power offers advantages for volumetric heating of biological tissues.

Purpose of the Study:

  • To review the state of the art in Microwave Cardiac Ablation (MCA).
  • To describe a novel catheter-based, unfurling wide aperture antenna for MCA.
  • To evaluate the efficacy of the novel antenna in creating therapeutic lesions.

Main Methods:

  • A novel spiral antenna design, insulated by a fluid-filled balloon, is deployed via catheter.
  • Microwave power (50-150 W) at 915 MHz is applied for 30-90 seconds to create lesions.

Related Experiment Videos

  • Simulated and experimental measurements were conducted on phantoms, ex vivo, and in vivo animal models.

    • Main Results:

    • The novel antenna successfully created irreversible lesions in cardiac tissue.
    • Lesions generated by MCA were wider and deeper compared to RF ablation.
    • The specialized antenna design minimized excessive surface heating.

    Conclusions:

    • The novel catheter-based microwave antenna is effective for treating cardiac arrhythmias.
    • MCA provides a precise and effective alternative to RF ablation for atrial fibrillation.
    • This technology demonstrates potential for improved minimally invasive cardiac ablation procedures.