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Related Experiment Videos

Raised Intracranial Pressure.

Eliahu S Feen1, Jose I Suarez

  • 1Neurosciences Critical Care, University Hospitals of Cleveland, 11100 Euclid Avenue, Hanna 5, Cleveland, OH 44106, USA. jose.suarez@uhhs.com.

Current Treatment Options in Neurology
|January 29, 2005
PubMed
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Raised intracranial pressure (ICP) is a critical concern in neurocritical care, often leading to death. Management involves immediate evaluation and therapies like controlled hyperventilation and hyperosmolar agents, with advanced options for refractory cases.

Area of Science:

  • Neurology
  • Neurosurgery
  • Critical Care Medicine

Background:

  • Raised intracranial pressure (ICP) is a frequent and life-threatening complication in neurocritically ill patients.
  • It is a primary driver of mortality in individuals with intracranial pathology.
  • A significant gap exists in controlled clinical trials for many current ICP management strategies.

Purpose of the Study:

  • To discuss the fundamental pathophysiologic and clinical principles of raised ICP.
  • To present the major therapeutic options for managing elevated ICP.
  • To highlight the immediate evaluation and treatment considerations for patients with raised ICP.

Main Methods:

  • Immediate patient evaluation focusing on airway and hemodynamic status.
  • Administration of controlled hyperventilation and hyperosmolar therapy (mannitol or hypertonic saline).

Related Experiment Videos

  • Consideration of advanced therapies for refractory ICP, including barbiturate coma and surgical interventions.

    • Main Results:

    • Immediate assessment of airway and hemodynamics is crucial for patients with raised ICP.
    • Simultaneous use of controlled hyperventilation and hyperosmolar agents is common practice.
    • Refractory ICP elevations may necessitate barbiturate coma or surgical interventions.

    Conclusions:

    • Prompt recognition and management of raised ICP are vital in neurocritical care.
    • A stepwise approach to ICP management, starting with basic interventions, is essential.
    • Further controlled clinical trials are needed to validate existing and emerging therapies for raised ICP.