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Updated: Aug 19, 2026
Biochemical Measurement of Neonatal Hypoxia
Published on: August 24, 2011
Carnitine levels in neonatal hypoxia
Halit Cam1, Behçet Yildirim, Ahmet Aydin
1Department of Pediatrics, Istanbul University, Cerrahpasa Medical Faculty. hacam@istanbul.edu.tr
Background:
The aim of this study is to determine carnitine levels in hypoxic-ischemiac neonates.
Methods:
Total and free carnitine levels were measured in 20 normal term neonates and 20 term neonates who were diagnosed as hypoxia-ischemia.
Results:
Both total carnitine levels (43.7 +/- 10.0 microg/dl vice 27.8 +/- 11.8 microg/dl, p<0.0001) and free carnitine levels (28.0 +/- 8.8 vice 13.2 +/- 6.8 microg/dl, p<0.0001) were lower in the hypoxic-ischemic group). Additionally acyl/total carnitine ratio was higher in the asphyxic group (0.33 +/- 0.20 vice 0.56 +/- 0.24, p<0.0001).
Conclusions:
The findings of this study show that neonates with hypoxia-ischemia suffer carnitine deficiency.
