Related Experiment Videos
The "steroid dementia syndrome": an unrecognized complication of glucocorticoid treatment
Owen M Wolkowitz1, Sonia J Lupien, Erin Bigler
1University of California, San Francisco, School of Medicine, 401 Parnassus Ave., Box F-0984, San Francisco, CA 94143-0984, USA. owenw@itsa.ucsf.edu
Abstract:
Glucocorticoid treatment is frequently associated with transiently impaired attention, concentration, and memory. In rare cases, cognitive changes may be prominent and may persist for substantial periods of time after steroid discontinuation. This largely unrecognized complication has been termed the "steroid dementia syndrome" and may reflect steroid neuroendangerment or neurotoxicity. Several clinical cases of this syndrome, with shared phenomenological and neuropsychological features, are presented here.
Related Concept Videos
Cushing Syndrome I: Introduction
Cushing Syndrome II: Pathophysiology
Dementia l: Introduction
Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids
Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids
ICS work through a multifaceted mechanism of action. They suppress the inflammatory response caused by the proliferation of TH cells. They also reduce the transcription of the IL-2 gene, which is involved in the...
COPD: Management Using Bronchodilators and Corticosteroids