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Automated impedance cardiography for detecting ischemic left ventricular dysfunction during exercise testing.

A Scherhag1, S Pfleger, E Garbsch

  • 1I. Medical Clinic, University Hospital Mannheim, Faculty of Clinical Medicine Mannheim, University of Heidelberg, Mannheim, Germany. armin.scherhag@roche.com

Kidney & Blood Pressure Research
|January 29, 2005
PubMed
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Automated impedance cardiography (ICG) reliably assesses cardiac function during exercise in suspected coronary artery disease (CAD). It identifies exercise-induced left ventricular dysfunction, aiding patient selection for interventions.

Area of Science:

  • Cardiovascular Physiology
  • Noninvasive Hemodynamic Monitoring
  • Diagnostic Imaging

Background:

  • Automated impedance cardiography (ICG) offers a noninvasive approach to hemodynamic evaluation.
  • Assessing cardiac function during exercise is crucial for diagnosing coronary artery disease (CAD).

Purpose of the Study:

  • To evaluate the feasibility and diagnostic utility of automated ICG in patients with suspected CAD.
  • To assess stroke index (SI) and cardiac index (CI) at rest and during exercise.

Main Methods:

  • Sixty-five patients with suspected CAD underwent automated ICG during rest and bicycle exercise testing.
  • Patients were categorized into groups based on coronary angiography (CA) findings: no CAD, single-vessel disease, or multivessel disease.
  • Automated ICG measurements were compared with thermodilution (TD) in a subset of 20 patients.

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Main Results:

  • Patients with multivessel disease (groups 2-3) exhibited significantly lower SI and CI during exercise compared to controls (p < 0.05).
  • Automated ICG showed good correlation with TD measurements for CI at rest (r=0.73) and during exercise (r=0.89-0.91).
  • Three patients were excluded due to signal quality issues during exercise.

Conclusions:

  • Automated ICG is feasible and practical for hemodynamic monitoring during exercise testing.
  • Automated ICG provides valuable diagnostic information on left ventricular (LV) function during exercise.
  • This method aids in selecting patients likely to benefit from coronary interventions.