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[Parry-Romberg's syndrome and epilepsy]
M Chbicheb1, A Gelot, F Rivier
1Service de Médecine C, Unité de Neurologie, Centre Hospitalier, Narbonne.
Revue Neurologique
|January 29, 2005
Summary
Parry-Romberg syndrome, a rare facial disorder, is often linked to epilepsy. A neurodevelopmental theory involving vascular issues is proposed to explain this association.
Area of Science:
- Neurology
- Genetics
- Dermatology
Background:
- Parry-Romberg syndrome (progressive facial hemiatrophy) is a rare condition of unknown cause.
- It frequently presents with neurological complications, notably focal refractory epilepsy.
- Associated brain lesions occur on the same side as facial atrophy and can progress.
Observation:
- Presents two cases of Parry-Romberg syndrome co-occurring with epilepsy.
- One patient underwent neurosurgery, allowing for histological examination.
Findings:
- Discusses the established link between Parry-Romberg syndrome and epilepsy.
- Suggests a neurodevelopmental theory involving vascular dysgenesis as a potential cause.
Implications:
- Highlights the importance of considering neurological complications in Parry-Romberg syndrome.
- Proposes a new etiological theory for further research into this rare condition.