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Updated: Aug 19, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
Midterm results of mitral valve repair with artificial chordae in children
Kazu Minami1, Hideaki Kado, Sadahiro Sai
1Department of Cardiovascular Surgery, Fukuoka Children's Hospital, Fukuoka, Japan.
Insights
Artificial chordal replacement using expanded polytetrafluoroethylene sutures is a safe and effective mitral valve repair in children, showing favorable midterm results and supporting patient growth.
Area of Science:
- Pediatric Cardiac Surgery
- Cardiovascular Surgery
- Medical Devices
Background:
- Mitral valve repair in children presents unique challenges due to growth and development.
- Expanded polytetrafluoroethylene (ePTFE) sutures offer a promising solution for artificial chordal replacement in pediatric mitral valve repair.
Purpose of the Study:
- To evaluate the midterm clinical outcomes of mitral valve repair using ePTFE sutures in pediatric patients.
- To assess the safety and efficacy of this technique in a pediatric population.
Main Methods:
- Retrospective analysis of 39 children undergoing mitral valve repair with ePTFE chordal replacement between April 1995 and September 2003.
- Patients had moderate or severe mitral regurgitation due to anterior mitral leaflet prolapse.
- Mean follow-up was 5.0 years.
Main Results:
- No operative or late deaths occurred.
- Only one patient required mitral valve replacement post-procedure.
- Actuarial freedom from reoperation was 94.8% at 5 years and 89.5% at 8 years.
- 84.6% of patients had trivial or less mitral regurgitation at latest follow-up.
Conclusions:
- Mitral valve repair with ePTFE sutures provides favorable midterm results in children.
- The procedure is safe and effective, accommodating for patient growth.
- This technique shows potential for long-term pediatric cardiac care.
Objective:
We have used artificial chordal replacement with expanded polytetrafluoroethylene sutures for mitral valve repair in children and reported favorable early clinical results. In this article we evaluate the midterm results of mitral valve repair with expanded polytetrafluoroethylene sutures in 39 children.
Methods:
From April 1995 through September 2003, mitral valve repair with chordal replacement using expanded polytetrafluoroethylene sutures was performed in 39 patients. In all patients the preoperative grade of mitral regurgitation was moderate or more because of prolapse of the anterior mitral leaflet. The mean age and body weight at the time of the operation were 4.7 +/- 5.3 years (range, 1 month to 17.8 years) and 14.4 +/- 12.2 kg (range, 3.9-54.4 kg), respectively. The number of expanded polytetrafluoroethylene sutures ranged from 1 to 3 (mean, 1.4). The mean follow-up period and body weight at the latest follow-up were 5.0 +/- 2.3 years (range, 1.1-8.5 years) and 25.7 +/- 16.4 kg (range, 6.9-73 kg), respectively.
Results:
There were no operative or late deaths. Only one patient required mitral valve replacement, which occurred 17 days after repair. Two patients underwent redo mitral valve repair 2 and 5 years after initial repair, respectively. The actuarial freedom from reoperation at 5 and 8 years was 94.8% and 89.5%, respectively. At the latest follow-up, trivial or less mitral regurgitation was observed in 33 (84.6%) patients.
Conclusions:
Mitral valve repair with expanded polytetrafluoroethylene sutures in children demonstrated favorable midterm outcome. The procedure is safe and effective, with potential for patients' growth.
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