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Two new hepatoprotective stilbene glycosides from Acer mono leaves
Hyekyung Yang1, Sang Hyun Sung, Young Choong Kim
1College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University, Sillim-Dong, Gwanak-Gu, Seoul 151-742, Korea.
Journal of Natural Products
|February 1, 2005
Abstract:
Two new stilbene glycosides, 5-O-methyl-(E)-resveratrol 3-O-beta-d-glucopyranoside (1) and 5-O-methyl-(E)-resveratrol 3-O-beta-D-apiofuranosyl-(1-->6)-beta-d-glucopyranoside (2), were isolated from the leaves of Acer mono, along with seven known compounds. Among these compounds, 1, 2, and quercetin (3) showed significant hepatoprotective activities against H(2)O(2)-induced toxicity in primary cultures of rat hepatocytes.
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