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A dotplot program for the Atari ST, for the analysis of DNA and protein sequences
1Department of Paediatrics, Academic Hospital Leiden, The Netherlands.
Abstract:
A program was written in GFA-BASIC for the Atari ST microcomputer aimed at drawing two-dimensional homology 'dotplot' patterns for two protein or DNA sequences. The program, built around a machine-code subroutine, communicates interactively with the user by means of a multi-button dialogue panel and mouse-directed input. A 1000 X 1000 sequence comparison with a 14:21 stringency window takes 12 s.