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Induction of Murine Intestinal Inflammation by Adoptive Transfer of Effector CD4+CD45RBhigh T Cells into Immunodeficient Mice
Published on: April 21, 2015
CD45 knockout mice, diet, and colitis: in the absence of CD45, colitis follows dietary changes
1Department of Pathology, University of Cambridge, Cambridge, CB2 1QP United Kingdom. lopezma@mail.amc.edu
Annals of the New York Academy of Sciences
|February 1, 2005
Abstract:
Healthy CD45 KO mice show a Th2-type cytokine secretion profile in their small intestines. Dietary supplementation with human infant formula induced colitis and a shift toward a Th1-type profile, suggesting that diet can alter cytokine secretion.
