Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Diastolic dysfunction.

Gordon A Ewy1

  • 1University of Arizona College of Medicine, 1501 N. Campbell Avenue, Room 6404, Tucson, AZ 85724, USA. gaewy@aol.com

Journal of Insurance Medicine (New York, N.Y.)
|February 3, 2005
PubMed
Summary

Diastolic dysfunction impairs heart relaxation, unlike systolic dysfunction which reduces contractility. Echocardiography, particularly assessing left atrial enlargement, helps distinguish these conditions, crucial for elderly patients with hypertension.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The mechanism of blood flow during chest compressions for cardiac arrest is probably influenced by the patient's chest configuration.

Acute medicine & surgery·2018
Same author

Do Not Resuscitate Tattoos.

The American journal of medicine·2018
Same author

Cardiocerebral and cardiopulmonary resuscitation - 2017 update.

Acute medicine & surgery·2017
Same author

A Natural Biomarker Deserving Attention: Gasping Following Primary Cardiac Arrest.

Journal of the American College of Cardiology·2017
Same author

Chest Compression Only Cardiopulmonary Resuscitation for Primary Cardiac Arrest.

Circulation·2016
Same author

The time dependent association of adrenaline administration and survival from out-of-hospital cardiac arrest.

Resuscitation·2015

Area of Science:

  • Cardiology
  • Cardiac Physiology
  • Diagnostic Imaging

Background:

  • Diastolic dysfunction is characterized by impaired ventricular relaxation, normal contractility, and ejection fraction.
  • Systolic dysfunction involves reduced contractility and ejection fraction, alongside impaired relaxation.
  • Both dysfunctions present similar clinical signs, necessitating accurate diagnostic methods.

Purpose of the Study:

  • To differentiate between diastolic and systolic heart dysfunction.
  • To identify reliable echocardiographic markers for diastolic dysfunction assessment.
  • To explore the role of biomarkers in heart failure diagnosis.

Main Methods:

  • Echocardiography was employed to assess left ventricular function and structure.
  • Left atrial (LA) volume indexed to body surface area was measured to evaluate diastolic function.
  • B-type natriuretic protein levels were considered for heart failure assessment.

Main Results:

  • Left atrial enlargement, defined as indexed LA volume ≥ 34-40 mL/m², is a key indicator of diastolic dysfunction.
  • Echocardiography is essential for distinguishing between diastolic and systolic dysfunction.
  • B-type natriuretic protein aids in heart failure diagnosis and prognosis but does not differentiate dysfunction types.

Conclusions:

  • Indexed left atrial volume is the most effective echocardiographic measure for assessing diastolic heart function.
  • Accurate differentiation between diastolic and systolic dysfunction is critical for appropriate patient management.
  • Further research into drug treatments targeting diastolic dysfunction mechanisms is ongoing.

Related Experiment Videos