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Updated: Aug 19, 2026

Technical Demonstration of Whole Genome Array Comparative Genomic Hybridization
Published on: August 5, 2008
CrossChip: a system supporting comparative analysis of different generations of Affymetrix arrays
Sek Won Kong1, Kyu-Baek Hwang, Richard D Kim
1Bauer Center for Genomics Research, Harvard University, Cambridge, MA, USA. skong@cgr.harvard.edu
Summary:
To increase compatibility between different generations of Affymetrix GeneChip arrays, we propose a method of filtering probes based on their sequences. Our method is implemented as a web-based service for downloading necessary materials for converting the raw data files (*.CEL) for comparative analysis. The user can specify the appropriate level of filtering by setting the criteria for the minimum overlap length between probe sequences and the minimum number of usable probe pairs per probe set. Our website supports a within-species comparison for human and mouse GeneChip arrays.
Availability:
http://www.crosschip.org
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