Related Experiment Video
Updated: Aug 19, 2026
Development of an In Vitro Ocular Platform to Test Contact Lenses
Published on: April 6, 2016
Clinical trial of a noninvasive contact lens glucose sensor
Wayne F March1, Achim Mueller, Peter Herbrechtsmeier
1Department of Ophthalmology, Downstate Health Science Center, State University of New York, Brooklyn, New York 11203-2098, USA. WFMarch47@aol.com
Objective:
The purpose of the present study was to determine the effectiveness of a fluorescent contact lens glucose sensor in monitoring glucose in patients with diabetes.
Methods:
Under an institutional review board-approved protocol, five fasting patients with type II diabetes were given a challenge consisting of 75 mL of Sustacal (Thomson Micromedex, Greenwood, CO) by mouth. Contact lens fluorescence and venous blood glucose were measured over a 3-h period.
Results:
Contact lens fluorescence appeared to track blood glucose well. The fluorescent daily-wear disposable contact lenses were comfortable and were tolerated well, even in patients who had not previously worn contact lenses.
Conclusion:
The contact lens glucose sensor shows promise as a home glucose monitor.
