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Devastating presentations of regional enteritis (Crohn's disease): two reports of survival following severe multiple
Catherine J Grossman1, Lynn J Hydo, John C L Wang
1Department of Surgery, Division of Critical Care and Trauma, Weill Medical College of Cornell University, New York, New York, USA.
Background:
Regional enteritis may present in the setting of a variety of clinical symptoms. These symptoms range from mild to severe.
Methods:
Here we describe two different presentations of regional enteritis (Crohn's disease): one in the setting of Clostridium perfringens sepsis and the second in association with hemolytic-uremic syndrome. Both presentations resulted in life-threatening multiple organ dysfunction syndrome.
Results:
Following appropriate surgical management and intensive physiologic support, both patients recovered, despite a MODS-predicted risk of mortality of 100% and 91%, respectively.
Conclusions:
Fulminant presentations of regional enteritis of this magnitude are rare, and highlight the resolution of severe multiple organ dysfunction for each presentation.
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