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Updated: Aug 19, 2026

Intratibial Osteosarcoma Cell Injection to Generate Orthotopic Osteosarcoma and Lung Metastasis Mouse Models
Published on: October 28, 2021
[Pulmonary metastases in osteosarcoma patients--treatment results]
Andrzej Szafrański1, Wojciech Woźniak, Magdalena Rychłowska-Pruszyńska
1Klinika Chirurgii Onkologicznej Dzieci i Młodziezy Instytutu Matki i Dziecka w Warszawie. szafran@supermedia.pl
Unlabelled:
In the Institute of Mother and Child in Warsaw, in the years 1985-2002, 382 osteosarcoma patients were treated. The ages of the patients were from 3 to 26 years old. 117 patients had metastases. The whole group of patients was divided into two groups. Treatment was begun from chemotherapy. When stabilization or partial regression was observed the operative procedures was made. In progression conservative treatment was used.
Results:
In the group of 18 patients for whose was used conservative treatment only, 2 children are alive. In the group of 99 patients that were treated surgical, 29 live. DFS--30%.
Conclusions:
1. In case of osteosarcoma is profitable to extract metastatic focus in the period of stabilization after chemotherapy. 2. Also it seems purposely even many times excision of metastases. 3. Operation of metastatic focus makes it possible for patients to live many years. 28% of our patients live fifth years after the end of the treatment.
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