Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jul 5, 2026

Origami Inspired Self-assembly of Patterned and Reconfigurable Particles
12:33

Origami Inspired Self-assembly of Patterned and Reconfigurable Particles

Published on: February 4, 2013

Mediator-template assembly of nanoparticles.

Mathew M Maye1, I-Im S Lim, Jin Luo

  • 1Department of Chemistry, State University of New York at Binghamton, Binghamton, NY 13902, USA.

Journal of the American Chemical Society
|February 3, 2005
PubMed
Summary

This study introduces a mediator-template strategy for assembling nanoparticles into controllable spherical structures. This method enables size control and offers potential for nanoelectronics and drug delivery applications.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Artificial Intelligence-Enhanced Optimization of Wireless Breath Sensor Arrays for Detection of Lung Cancer Using Fuzzy Logic-Guided Genetic Algorithm and Multimodal Machine Learning.

ACS sensors·2026
Same author

Plasmonic Nanoprobe-Enabled SERS Detection of SARS-CoV-2 Proteins and Virus Samples on Wax-Printed Paper Substrates.

Analytical chemistry·2025
Same author

Atomic Spreading and Retraction of Supported Ultrasmall Alloy Nanoparticles under Reactive Oxygen at Elevated Temperatures.

Journal of the American Chemical Society·2025
Same author

In Situ/Operando Probing of Dynamic Phase Structures of Alumina-Supported Ultrasmall Copper-Gold Alloy Nanoparticles Under Reaction Conditions.

Angewandte Chemie (International ed. in English)·2025
Same author

Probing Interfacial Nanostructures of Electrochemical Energy Storage Systems by In-Situ Transmission Electron Microscopy.

Nano-micro letters·2025
Same author

Obstetric and neonatal outcomes in clinically diagnosed placental abruption with and without placental histopathologic confirmation-A retrospective study.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics·2025

Area of Science:

  • Nanotechnology
  • Materials Science
  • Chemical Engineering

Background:

  • Controlling nanoparticle assembly is crucial for developing advanced nanomaterials.
  • Existing methods often lack precise control over size and shape.
  • Nanoparticle-structured properties depend heavily on their assembly.

Purpose of the Study:

  • To investigate a mediator-template strategy for size-controllable nanoparticle assembly.
  • To prepare size-controllable and monodispersed spherical nanoparticle assemblies.
  • To explore the potential applications of these assemblies in various fields.

Main Methods:

  • Utilizing multidentate thioether ligands as molecular mediators.
  • Employing tetraalkylammonium-capped gold nanoparticles (5 nm) as templates.

More Related Videos

Nanomoulding of Functional Materials, a Versatile Complementary Pattern Replication Method to Nanoimprinting
10:49

Nanomoulding of Functional Materials, a Versatile Complementary Pattern Replication Method to Nanoimprinting

Published on: January 23, 2013

ECM Protein Nanofibers and Nanostructures Engineered Using Surface-initiated Assembly
16:33

ECM Protein Nanofibers and Nanostructures Engineered Using Surface-initiated Assembly

Published on: April 17, 2014

Related Experiment Videos

Last Updated: Jul 5, 2026

Origami Inspired Self-assembly of Patterned and Reconfigurable Particles
12:33

Origami Inspired Self-assembly of Patterned and Reconfigurable Particles

Published on: February 4, 2013

Nanomoulding of Functional Materials, a Versatile Complementary Pattern Replication Method to Nanoimprinting
10:49

Nanomoulding of Functional Materials, a Versatile Complementary Pattern Replication Method to Nanoimprinting

Published on: January 23, 2013

ECM Protein Nanofibers and Nanostructures Engineered Using Surface-initiated Assembly
16:33

ECM Protein Nanofibers and Nanostructures Engineered Using Surface-initiated Assembly

Published on: April 17, 2014

  • Characterizing assembly morphology using Transmission Electron Microscopy (TEM), Atomic Force Microscopy (AFM), and Small-Angle X-ray Scattering (SAXS).
  • Analyzing optical properties via dynamic light scattering and spectrophotometry.

    • Main Results:

    • Successfully prepared monodispersed spherical assemblies with diameters ranging from approximately 20-300 nm.
    • Demonstrated the role of mediator and template forces in establishing interparticle linkage and stability.
    • Characterized the soft-hard nature of assemblies and their substrate interactions.
    • Observed tunable light scattering and optical absorption properties based on assembly parameters.
    • Achieved controlled disassembly into individual nanoparticles and size regulation using a third capping component.

    Conclusions:

    • The mediator-template strategy is a versatile technique for nanoparticle assembly.
    • The developed assemblies show promise for nanoscale linkages, nanoelectronics, nanosensor devices, and controlled drug delivery.
    • Further research can explore the fundamental correlations between morphological, optical properties, and assembly parameters.