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Updated: Aug 19, 2026
07:03
Imaging Denatured Collagen Strands In vivo and Ex vivo via Photo-triggered Hybridization of Caged Collagen Mimetic Peptides
Published on: January 31, 2014
Structure-based design of potent and selective inhibitors of collagenase-3 (MMP-13)
Soong-Hoon Kim1, Andrew T Pudzianowski, Kenneth J Leavitt
1Bristol Myers Squibb Co., Pharmaceutical Research Institute, PO Box 4000, Princeton, NJ 08560, USA. soonghoon.kim@bms.com
Bioorganic & Medicinal Chemistry Letters
|February 3, 2005
Abstract:
Computer aided drug design led to a new class of spiro-barbiturates (e.g., 4a, MMP-13 K(i)=4.7 nM) that are potent inhibitors of MMP-13.
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