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Optimized Interferon-gamma ELISpot Assay to Measure T Cell Responses in the Guinea Pig Model after Vaccination
Published on: January 20, 2019
Mouse and guinea pig models for testing new tuberculosis vaccines
1Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523, USA. iorme@lamar.colostate.edu
Tuberculosis (Edinburgh, Scotland)
|February 3, 2005
Abstract:
Animal models of pulmonary tuberculosis in the mouse and guinea pig contain to provide new information about the host response in the lungs, changes in immunopathology, and the protective effect of new vaccine candidates. These include Mtb72F, a polyprotein vaccine that gives excellent protection and also boosts and prolongs the protective effect of the BCG vaccine.

