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Percutaneous breast biopsy for nonpalpable lesions
G A DeAngelis1, L L Fajardo, J A Harvey
1Department of Radiology, University of Virginia, Charlottesville, VA, USA. giaann@virginia.edu
Breast Disease
|February 3, 2005
Summary
Percutaneous core-needle biopsies are increasingly used for breast abnormalities, offering accuracy and reduced morbidity compared to surgical excisions. Careful management ensures accurate diagnosis and appropriate follow-up screening.
Area of Science:
- Radiology
- Pathology
- Oncology
Background:
- Percutaneous core-needle biopsy is replacing surgical excision and fine-needle aspiration (FNA) for breast abnormality diagnosis.
- Core-needle biopsies offer high accuracy and reduced patient morbidity and healthcare costs.
Purpose of the Study:
- To discuss equipment and techniques for stereotactic and ultrasound-guided core breast biopsy.
- To provide guidance on appropriate indications for different biopsy methods.
- To outline management strategies following core-needle biopsy.
Main Methods:
- Review of equipment and techniques for stereotactic and ultrasound-guided core breast biopsy.
- Discussion of indications for core-needle biopsy, excisional biopsy, and FNA.
- Emphasis on correlating histologic findings with mammographic suspicion.
Main Results:
- Core-needle biopsies are highly accurate, reducing morbidity and cost in breast disease diagnosis.
- A key limitation is differentiating atypical ductal hyperplasia from ductal carcinoma in situ.
- Concordance between histology and mammography is crucial to prevent false-negative results.
Conclusions:
- Management after core-needle biopsy depends on correlating histologic results with mammographic findings.
- Recommendations for follow-up range from regular screening to repeat biopsy or surgery.
- Accurate diagnosis through core-needle biopsy is essential for timely and appropriate breast cancer management.
