[Other surgical therapies for cornea burns]

With limbal stem cell and amniotic membrane transplantations, penetrating keratoplasty is the most important treatment of severe corneal burns. In the acute stage, re-epithelialization failure and resultant stromal ulceration can induce corneal perforation. A lamellar or a full-thickness patch graft is indicated in order to preserve the eyeball. For small perforations, tissue adhesive can be used. In the early reparative stage, keratoplasty has its place, but corneal vascularization is a major risk factor for graft rejection. Lamellar keratoplasty is preferred because it provides tectonic support. After several graft failures, a keratoprosthesis is the last solution for these bilaterally affected patients, but evisceration cannot be always avoided.