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Updated: Aug 19, 2026

Assessing Changes in Volatile General Anesthetic Sensitivity of Mice after Local or Systemic Pharmacological Intervention
Published on: October 16, 2013
[Advancements in pharmacology of and pharmacotherapy with local anaesthetics]
Irina Grădinaru1, M Nechifor, Monica Tatarciuc
1Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi, Facultatea de Medicină Dentară, Departamentul de Reabilitare Orală Complexă.
Abstract:
The local anaesthetic domain, very often implicated in the dental practice, it's in to a continuously progress from two points of view: the development of the products proposal and the improvement of the pharmacokinetic parameters. In our study we presented: new classifications of local anaesthetics, their characteristics and structure, the pharmacokinetic and pharmacodynamic parameters of local anaesthetics used in dental practice. An interesting remark of last years is represented by the fact that the local anaesthetics could also have an antibacterial effect which is often helpful in dental practice.
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