Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Castleman's disease with diffuse cervical localisation: case report.

T Minerva1, R Franza, D Panico

  • 1"Card G Panico" Hospital, Tricase, Lecce, Italy.

Acta Otorhinolaryngologica Italica : Organo Ufficiale Della Societa Italiana Di Otorinolaringologia E Chirurgia Cervico-Facciale
|February 4, 2005
PubMed
Summary

Castleman's disease, a rare lymphoid disorder, can affect the neck. This study describes a unique diffuse cervical form with a benign 7-year outcome, suggesting potential immunological links.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prospective multicentre study on azole resistance in Aspergillus isolates from surveillance cultures in haematological patients in Italy.

Journal of global antimicrobial resistance·2020
Same author

Innate and adaptive immunity in patients with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy.

Mycoses·2008
Same author

Myiasis of the tracheostomy wound: case report.

Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale·2008
Same author

Rhodotorula mucilaginosa outbreak in neonatal intensive care unit: microbiological features, clinical presentation, and analysis of related variables.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology·2006
Same author

A severe case of Yersinia enterocolitica infection in a thalassemic patient.

Italian journal of gastroenterology and hepatology·1997
Same author

[Comparative clinical data on the bronchodilating effect of some selective beta-2 stimulating drugs].

La Pediatria·1977

Area of Science:

  • Hematology
  • Immunology
  • Pathology

Background:

  • Castleman's disease is a rare lymphoid proliferation with varied locations.
  • Predominantly mediastinal, it can occur in any lymph node or extra-nodal site.
  • Over 500 cases reported, with only 57 in the cervical region.

Observation:

  • This case presents diffuse cervical lymph-node hyperplasia, not a solitary mass.
  • Histology revealed a hyaline-vascular type with a plasma-cellular component.
  • The patient experienced a benign 7-year evolution without surgical intervention.

Findings:

  • Low B and T4 lymphocyte counts suggest an immunological basis for Castleman's disease.
  • The observed diffuse cervical hyperplasia represents a distinct subtype.

Related Experiment Videos

  • The condition showed a benign clinical course over seven years.

    • Implications:

    • Castleman's disease in the cervical site may require classification into single-mass and multicentric subtypes.
    • Findings suggest a potential role for immunological dysregulation in cervical Castleman's disease.
    • Further research into the pathogenesis and classification of cervical Castleman's disease is warranted.