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Acne fulminans.

Khosrow Mehrany1, Joseph M Kist, Roger H Weenig

  • 1Department of Dermatology, Mayo Clinic, Rochester, MN 55905, USA.

International Journal of Dermatology
|February 4, 2005
PubMed
Summary
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Acne fulminans is a rare, severe skin condition. This case report details a rare instance of acne fulminans occurring after a patient stopped taking isotretinoin and prednisone.

Area of Science:

  • Dermatology
  • Rheumatology
  • Internal Medicine

Background:

  • Acne fulminans is a rare syndrome characterized by severe necrotizing acne, bone lesions, and systemic symptoms.
  • It is often associated with specific laboratory abnormalities, indicating a significant inflammatory process.

Observation:

  • This report presents a case of acne fulminans in an adolescent male.
  • The condition developed subsequent to the withdrawal of isotretinoin and prednisone treatments.

Findings:

  • The case highlights a potential, albeit rare, adverse reaction to medication withdrawal in acne management.
  • This specific sequence of events (drug withdrawal followed by acne fulminans) is not commonly documented.

Implications:

Related Experiment Videos

  • Understanding this association is crucial for clinicians managing patients with severe acne, particularly those on or recently withdrawn from potent therapies.
  • Further investigation may be warranted to elucidate the mechanisms linking medication withdrawal to acne fulminans.
  • This case underscores the importance of monitoring patients closely during and after treatment for severe acne, especially when using medications like isotretinoin and corticosteroids.