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Actinic granuloma successfully treated with acitretin
C Stefanaki1, A Panagiotopoulos, P Kostakis
1Third Department, Andreas Sygros Skin Hospital, Athens, Greece. cstefana@otenet.gr
International Journal of Dermatology
|February 4, 2005
Summary
Actinic granuloma, a rare solar radiation-induced skin condition, presents as annular patches. Acitretin treatment demonstrated significant improvement in a patient with this condition.
Area of Science:
- Dermatology
- Cutaneous Oncology
Background:
- Actinic granuloma is a rare skin disorder linked to actinic elastosis and solar radiation exposure.
- Its pathogenesis remains unclear, but sun exposure is the primary suspected trigger.
- The condition typically affects middle-aged individuals on sun-exposed skin.
Observation:
- The case involves a 74-year-old male with asymptomatic annular atrophic plaques on the forehead and nose.
- Lesions had been present for 8 months with insidious spread.
- Clinical diagnosis of actinic granuloma was confirmed via biopsy, excluding other conditions.
Findings:
- The patient received acitretin 25 mg/day for treatment.
- Remarkable improvement was observed within one year.
- Lesions ceased spreading and nearly disappeared.
Implications:
- Acitretin shows promise as an effective treatment for actinic granuloma.
- Further research into actinic granuloma pathogenesis and treatment is warranted.
- This case highlights a successful therapeutic approach for a rare dermatosis.