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Updated: Aug 19, 2026

Microbiologically Induced Calcite Precipitation Mediated by Sporosarcina pasteurii
Published on: April 16, 2016
[Corneal precipitation of fluoroquinolones with magnesium]
X Parent1, A Marchal, J C Patillon
1Service de biochimie, Centre hospitalier Pasteur, Colmar. xavier.parent@ch-colmar.rss.fr
Abstract:
Infrared spectrophotometric analysis (FTIR) was performed on a crystalline deposit developed in a corneal ulcer by an old woman who received ciprofloxacine ophthalmic drops. We collected the data of the literature on the subject. After in vitro crystallization experiments, we conclude that ciprofloxacin and norfloxacin corneal precipitates occur at physiological lachrymal pH with magnesium.
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