Related Experiment Video
Updated: Jul 29, 2026

Using the Activity-based Anorexia Rodent Model to Study the Neurobiological Basis of Anorexia Nervosa
Published on: October 22, 2015
Pattern of birth in early-onset anorexia nervosa: an equatorial study
Kate Willoughby1, Rebecca Bowen, Ee-Lian Lee
1Department of Mental Health, St. George's Hospital Medical School, University of London, London, United Kingdom. k.willoughby@sghms.ac.uk
Objective:
Patients with anorexia nervosa (AN) born in the northern and southern hemispheres are more likely to be born during spring months than at any other time of the year. It has been hypothesized that environmental temperature at the time of conception may have a significant role in this pattern of findings. The current study aims to investigate the pattern of birth of early-onset AN patients in an equatorial region (Singapore), where there is little difference in environmental temperature throughout the year.
Method:
Dates of birth were collected for 102 patients who were born in Singapore and diagnosed with early-onset AN. The patterns of birth were analyzed using chi-square analysis.
Results:
There was no difference across the year in the birth patterns of patients with early-onset AN in Singapore, nor were there any differences between patients with restrictive and binge/purge AN.
Discussion:
This lack of seasonal variation in the equator adds support to the "temperature at conception" hypothesis.
Related Concept Videos
Pedigree Analysis
Anatomy of the Intestines
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the small...
Nondisjunction

