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Updated: Aug 19, 2026

Neutrophil Lifespan Extension with CLON-G and an In Vitro Spontaneous Death Assay
Published on: May 12, 2023
[Clostridium infections in leukemias and malignant neoplasms]
Grzegorz Wallner1, Paweł Misiuna, Wiesław Cygan
1II Katedra i Klinika Chirurgii Ogólnej Akademii Medycznej w Lublinie. wallner@panaceum.am.lublin.pl
Abstract:
This review describes the subject of clostridial complications in leukemia and malignant neoplasms. These complications include bacteremia and spontaneous nontraumatic gas gangrene of the muscles. The mechanism of anaerobic microenvironment formation, which is necessary for infection development in neoplastic tumors, is also demonstrated. The role of risk factors contributing to the occurrence of clostridial infections is discussed. Further, the etiology of infections, related mostly to the action of Clostridium septicum and Clostridium perfringens toxins, as well as the pathogenesis of complications and their clinical course are indicated. Present treatment strategies are also briefly described.
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