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Management of lentigo maligna.
1Department of Dermatology, Mayo Clinic, Rochester, MN, USA.
Dermatology Nursing
|February 5, 2005
Summary
Lentigo maligna melanoma, a slow-growing skin cancer on sun-damaged skin, can invade deeper tissues. Wide-margin Mohs surgery with clear margin confirmation is the recommended treatment.
Area of Science:
- Dermatology
- Oncology
- Surgical Pathology
Background:
- Lentigo maligna melanoma (LMM) is a subtype of melanoma in situ.
- It typically affects sun-exposed areas like the head and neck in older individuals.
- LMM presents as a flat, pigmented lesion and has the potential for invasive growth.
Purpose of the Study:
- To review reported treatment options for lentigo maligna melanoma.
- To recommend an optimal treatment strategy for LMM.
Main Methods:
- Comprehensive review of existing literature on LMM treatments.
- Evaluation of surgical and pathological outcomes for various therapeutic approaches.
Main Results:
- Multiple treatment modalities for LMM have been reported in the literature.
- Wide-margin Mohs micrographic surgery demonstrated high efficacy in achieving clear margins.
Conclusions:
- Wide-margin Mohs micrographic surgery, coupled with peripheral permanent pathologic confirmation of a clear margin, is the recommended treatment of choice for lentigo maligna melanoma.
- This approach offers the best chance for complete eradication and minimizes recurrence risk.