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Related Experiment Videos

Adult choledochal cyst.

Kit Fai Lee1, Eric C H Lai, Paul B S Lai

  • 1Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China.

Asian Journal of Surgery
|February 5, 2005
PubMed
Summary

Malignancy complicating choledochal cysts in adults has a poor prognosis despite surgery. Older males with jaundice or impaired liver function should be suspected of malignancy.

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Area of Science:

  • Hepatobiliary Surgery
  • Surgical Oncology
  • Gastroenterology

Background:

  • Choledochal cysts are rare in adults.
  • Malignancy in choledochal cysts carries a poor prognosis.
  • Adult choledochal cyst management requires careful consideration of malignancy risk.

Purpose of the Study:

  • Review clinical course and operative results of adult choledochal cysts.
  • Emphasize the occurrence and impact of malignancy.
  • Evaluate outcomes of surgical management in adults.

Main Methods:

  • Retrospective review of adult patients undergoing surgery for choledochal cysts over 12 years.
  • Analysis of patient demographics, previous procedures, and malignancy status.
  • Comparison of outcomes between benign and malignant cases.

Main Results:

  • 20% of adult choledochal cyst patients (25 total) had malignancy.
  • Malignancy was more common in older males with impaired liver function.
  • No operative mortality, but 36% operative morbidity; 3/5 malignancy patients died or recurred post-op.

Conclusions:

  • Prognosis for malignant choledochal cysts remains poor despite radical surgery.
  • Suspect malignancy in older males with jaundice or abnormal LFTs.
  • Total cyst excision and hepaticojejunostomy is effective for Type I cysts to prevent malignancy.

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