Related Experiment Video
Updated: Aug 19, 2026

Industrialized, Artificial Intelligence-guided Laser Microdissection for Microscaled Proteomic Analysis of the Tumor Microenvironment
Published on: June 3, 2022
Analysis of 197 female scalp tumors treated with Mohs micrographic surgery
Tracy M Katz1, Sirunya Silapunt, Leonard H Goldberg
1DermSurgery Associates, Houston, Texas 77030, USA.
Background:
There has been no previously published study on skin cancers on the scalp of women.
Objectives:
To better elucidate the characteristics of skin cancers that develop on the female scalp.
Methods:
A retrospective review of 13,885 biopsy-proven skin cancers treated by Mohs micrographic surgery was performed. We identified 197 tumors on the scalp of women. Demographic features and tumor characteristics were compiled and analyzed.
Results:
The average age of women with scalp tumors was 61.8 +/- 16.9, which was significantly lower than that of men with scalp tumors. The age followed a bimodal distribution with peaks in the fifth and eighth decades. Overall, 77% of female scalp tumors were basal cell carcinomas (BCCs), 17% were squamous cell carcinomas (SCCs), and 6% were a variety of other tumors. This contrasts with men in whom 53% of tumors were squamous cell carcinomas. Basal cell carcinomas were significantly more common in women under age 50.
Conclusion:
Skin cancers of the female scalp tend to be basal cell carcinomas, many of which occur at a relatively young age as compared to other skin cancers. The exact role of ultraviolet radiation in the development of some of these tumors is unclear.
