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Cutaneous Waldenstrom's macroglobulinemia with "deck-chair" sign treated with cyclophosphamide
Julien Autier1, Marc Buffet, Laure Pinquier
1Departments of Dermatology, Hôpital Tarnier-Cochin, Paris, France.
Journal of the American Academy of Dermatology
|February 5, 2005
Abstract:
Specific skin lesions are rare in Waldenstrom's macroglobulinemia (WM). We report a case of a 58-year-old man who presented macules, papules, and an erythema of the trunk with the "deck-chair" sign revealing the relapse of WM. Histologic and immunohistochemical examinations confirmed that cutaneous lesions were related to specific infiltration with neoplastic cells. Remission of both skin lesions and immunological abnormalities was obtained with oral cyclophosphamide.