Bile acid and sterol solubilization in 2-hydroxypropyl-beta-cyclodextrin
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J De Caprio1, J Yun, N B Javitt
1Division of Hepatic Diseases, New York University Medical Center 10016.
Journal of Lipid Research
|March 1, 1992
Abstract:
The use of 2-hydroxypropyl-beta-cyclodextrin has made it possible to prepare stable aqueous solutions of cholesterol, 26-hydroxycholesterol, 7 alpha-hydroxycholesterol, and monohydroxy bile acids such as lithocholic and 3 beta-hydroxy-5-cholenoic acids. These solutions are suitable for cell culture studies and for parenteral administration to animals.