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[Predictive value of fetal fibronectin for preterm labor]
Enrique Gómez-Bravo Topete1, Claudia Castillo-Lechuga, Alvaro Villegas-Su
1Hospital Nicolás San Juan, ISEM.
Objective:
We evaluated fetal fibronectin levels for the diagnosis of preterm labor.
Material And Methods:
We included 74 randomized patients who were admitted with the diagnosis of preterm labor. Cervical and vaginal fluid samples were washed in buffer solution prior to the introduction of a reactive strip. Results were interpreted after 10 sec. Patients with negative tests were admitted and followed up. Patients who tested positive were treated according to the protocols of each hospital. Finally, the specificity, sensitivity, predictive value, and odds ratio were determined.
Results:
Results showed specificity, 90%; sensitivity, 70%; positive predictive value, 64%; negative predictive value, 78%; and odds ratio, 22; 50% were first pregnancies with gestational ages between 22 and 34 weeks.
Conclusions:
We consider that a positive fibronectin test is a useful, low-cost, and reliable tool for diagnosing preterm labor.
