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Updated: Aug 19, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Mitral valve morphology and morbidity/mortality in Shone's complex
Catherine M Ikemba1, Benjamin W Eidem, J Kennard Fraley
1University of Texas Southwestern, Children's Medical Center of Dallas, Division of Cardiology, Dallas, Texas, USA. catherine.ikemba@childrens.com
Insights
Shone
Area of Science:
- Cardiology
- Pediatric Cardiology
- Echocardiography
Background:
- Shone's complex is a rare congenital heart defect.
- Early identification of risk factors is crucial for managing Shone's complex.
Purpose of the Study:
- To identify echocardiographic features predicting progressive mitral valve disease and mortality in Shone's complex.
- To evaluate the prognostic value of specific left-sided cardiac anomalies.
Main Methods:
- Retrospective analysis of echocardiographic data from 50 patients with Shone's complex.
- Assessment of mitral valve morphology, chordal structure, and associated flow dynamics.
- Correlation of echocardiographic findings with the need for intervention and mortality.
Main Results:
- Thickened mitral valve leaflets and shortened chordae were associated with poor outcomes.
- Left ventricular outflow tract obstruction (without coarctation) and aortic insufficiency also predicted a worse prognosis.
- Color Doppler findings of turbulence at or below the mitral valve were significant.
Conclusions:
- Specific echocardiographic features in early childhood can predict the need for intervention and mortality in Shone's complex.
- Early identification of these features allows for timely management and improved patient outcomes.
Abstract:
Early echocardiographic studies of 50 patients with Shone's complex were retrospectively examined to identify left-sided cardiac features associated with progressive mitral valve (MV) disease requiring intervention, as well as mortality. Thickened MV leaflets, shortened MV chordae coupled with either thickened MV leaflets or turbulence at or below the MV noted by color Doppler, left ventricular outflow tract obstruction without coarctation of the aorta, and mild or moderate aortic insufficiency were associated with a poor prognosis.
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