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Plastic explosive poisoning in dogs.

K G De Cramer1, R P Short

  • 1Greenhills Veterinary Clinic, Republic of South Africa.

Journal of the South African Veterinary Association
|March 1, 1992
PubMed
Summary

Plastic explosive type 4 (PE4) is neurotoxic and can be fatal to dogs, causing symptoms similar to strychnine poisoning. Even small amounts of PE4 can lead to severe health issues and death in canine subjects.

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Area of Science:

  • Veterinary Toxicology
  • Animal Health
  • Explosives Safety

Background:

  • Plastic explosive type 4 (PE4) is a military-grade explosive.
  • Cyclonite is a primary component of PE4.
  • Accidental ingestion of explosives by animals poses a risk.

Observation:

  • A dog presented with signs of intoxication including fever, rapid pulse, and convulsions.
  • The dog had a suspected history of ingesting small amounts of PE4.
  • Clinical signs included congested mucous membranes, hyperventilation, and hypersensitivity.

Findings:

  • Experimental PE4 poisoning in a dog confirmed its neurotoxic effects.
  • A lethal dose was determined to be 14 mg/kg, causing death within 18 hours.
  • Post-mortem findings were consistent with strychnine poisoning.

Implications:

  • PE4 poses a significant toxicological risk to canines.
  • Veterinarians should be aware of PE4 toxicity symptoms.
  • This study highlights the need for secure explosive storage to prevent animal exposure.

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