Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Sentinel node biopsy can replace four-node-sampling in staging early breast cancer.

T Agarwal1, S K Kakkos, D A Cunningham

  • 1Breast Unit, St. Mary's Hospital, Praed Street, London W2 1NY, UK.

European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
|February 9, 2005
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Quality assessment of online patient information on upper gastrointestinal endoscopy using the modified Ensuring Quality Information for Patients tool.

Annals of the Royal College of Surgeons of England·2024
Same author

Do national policies for complaint handling in English hospitals support quality improvement? Lessons from a case study.

Journal of the Royal Society of Medicine·2022
Same author

Trends and associated factors for Covid-19 hospitalisation and fatality risk in 2.3 million adults in England.

Nature communications·2022
Same author

'Dear Doctor': a randomised controlled trial of a text message intervention to reduce burnout in trainee anaesthetists.

Anaesthesia·2022
Same author

Assessment of the introduction of semi-digital consent into surgical practice.

The British journal of surgery·2021
Same author

Investigating the Role of Diet and Exercise in Gut Microbe-Host Cometabolism.

mSystems·2020

Sentinel node (SN) biopsy is a sensitive method for breast cancer staging. In patients with identified SN, four-node axillary sampling offers no additional diagnostic information.

Area of Science:

  • Oncology
  • Surgical Pathology

Background:

  • Four-node axillary sampling is a standard method for axillary staging in the UK for breast cancer.
  • Sentinel node (SN) biopsy is an alternative staging technique.

Purpose of the Study:

  • To evaluate the sensitivity of sentinel node (SN) biopsy.
  • To compare SN biopsy with four-node axillary sampling for breast cancer staging.

Main Methods:

  • SN identification was attempted in 234 patients with unifocal breast cancers using isotope-labelled nanocolloid and patent blue dye.
  • SN were identified in 94.5% of patients.
  • All patients had four-node sampling; those with positive SN on frozen section (FS) underwent axillary clearance.

Main Results:

Related Experiment Videos

  • An average of 1.38 SN were identified per patient.
  • Histological examination of SN alone identified all node-positive patients detected by four-node sampling.

    • Conclusions:

    • Sentinel node biopsy is highly effective for axillary staging in breast cancer.
    • Four-node axillary sampling provides no additional information when SN are successfully identified.