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Updated: Aug 14, 2026
The Influence of Liver Resection on Intrahepatic Tumor Growth
Published on: April 9, 2016
Neoadjuvant chemotherapy does not increase postoperative complication rate after resection of colorectal liver
1Department of Surgery, University of Erlangen, Krankenhausstr. 12, D-91054 Erlangen, Germany. suleyman.yedibela@chir.med.uni-erlangen.de
Background:
This paper discusses, whether neoadjuvant chemotherapy has an impact on the rate of postoperative complications after primary resection of liver metastases from colorectal carcinoma.
Methods:
Of 183 patients 64 were studied. The patients were subdivided into two matched groups of 32 patients each-prior neoadjuvant chemotherapy (CT-group) vs. (control-group, primary resection).
Results:
There were no postoperative complications in 24 patients of the control group (75%) and 26 patients of the CT-group (81%). Following prior chemotherapy, no major complications such as liver failure were observed, even after extended resections.
Conclusion:
Neoadjuvant chemotherapy prior to surgical resection of colorectal liver metastases does not result in an increase of postoperative morbidity and mortality.
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