Cerebrovascular abnormalities in a population of children with neurofibromatosis type 1
Tena L Rosser1, Gilbert Vezina, Roger J Packer
1Department of Neurology, Center for Neuroscience and Behavioral Medicine, Children's National Medical Center, The George Washington University, 111 Michigan Avenue NW, Washington, DC 20010, USA. trosser@cnmc.org
Neurology
|February 9, 2005
Abstract:
Neurofibromatosis type 1 (NF1) is associated with vasculopathy, which may result in a variety of cerebrovascular complications. The purpose of this study was to evaluate the spectrum of cerebrovascular disease in a pediatric population with NF1. Of 316 patients with NF1 who underwent brain MRI, 8 (2.5%) children were reported to have an abnormality of the cerebrovascular system, including narrowed or ectatic vessels, vascular stenoses, aneurysm, and moyamoya.
