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Updated: Jul 21, 2026

Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients
Published on: December 18, 2016
Resective surgery to treat refractory status epilepticus in children with focal epileptogenesis
A Alexopoulos1, D K Lachhwani, A Gupta
1Department of Neurology, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA.
Abstract:
Prolonged high-dose suppressive therapy (HDST) is a mainstay in the management of refractory status epilepticus (RSE), albeit with high morbidity and mortality. The authors studied 10 patients who were carefully selected for epilepsy surgery after failing prolonged (>2 weeks) HDST. Status epilepticus was stopped acutely in all of them with no mortality and no substantial morbidity. At follow-up (median 7 months), 7 (70%) of 10 patients were seizure free, and 3 (30%) of 10 had significant improvement in their epilepsy.
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