Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Measuring pulsatile forces on the human cranium.

Cory S Goldberg1, Oleh Antonyshyn, Rajiv Midha

  • 1Division of Plastic Surgery and the Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada.

The Journal of Craniofacial Surgery
|February 9, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reducing Cartilage Warp in Nasal Reconstruction: The Role of Collagen and Proteoglycans.

Plastic and reconstructive surgery. Global open·2026
Same author

HSR26-232: Disparities in ICU Utilization and Mortality in Tumor Lysis Syndrome: Evaluating Equity in Supportive Care Per NCCN Guidelines.

Journal of the National Comprehensive Cancer Network : JNCCN·2026
Same author

HSR26-265: Adherence to NCCN Guidelines for Psychosocial Distress Management: Impact of Psychiatric Comorbidities on Inpatient Outcomes in Metastatic Cancer.

Journal of the National Comprehensive Cancer Network : JNCCN·2026
Same author

HSR26-265: Adherence to NCCN Guidelines for Psychosocial Distress Management: Impact of Psychiatric Comorbidities on Inpatient Outcomes in Metastatic Cancer.

Journal of the National Comprehensive Cancer Network : JNCCN·2026
Same author

HSR26-232: Disparities in ICU Utilization and Mortality in Tumor Lysis Syndrome: Evaluating Equity in Supportive Care Per NCCN Guidelines.

Journal of the National Comprehensive Cancer Network : JNCCN·2026
Same author

Core outcomes in nerve surgery: development of a core outcome set for lateral femoral cutaneous neuropathy.

Journal of neurosurgery·2026
Same journal

Clinical Manifestation of Congenital Unilateral Lower Lip Palsy: A Study of 111 Patients.

The Journal of craniofacial surgery·2026
Same journal

Racial and Regional Differences of the Cheek for Facial Feminization: A Systematic Review.

The Journal of craniofacial surgery·2026
Same journal

A Comparative Study Between the Modified Septal Extension Graft Based on the L-Strut Septum and the Costal Cartilage Graft Based on an Intact Native Septum in Nasal Plasty.

The Journal of craniofacial surgery·2026
Same journal

Does Angular Sagittal Split Osteotomy of the Mandibular Ramus Alter Fracture Patterns Compared With the Modifications of Posnick, Wolford, and Hunsuck/Epker?

The Journal of craniofacial surgery·2026
Same journal

Why Straight and Curved Platysma Morphologies May Produce Opposite Clinical Effects?

The Journal of craniofacial surgery·2026
Same journal

Does Preoperative Aprepitant Reduce Nausea and Emesis After Orthognathic Surgery?

The Journal of craniofacial surgery·2026
See all related articles

Cranial stresses from brain pulsation were quantified for the first time. These forces may cause material fatigue in cranioplasty implants, impacting craniofacial development and repair.

Area of Science:

  • Biomedical Engineering
  • Neuroscience
  • Materials Science

Background:

  • Cyclic stresses from brain pulsation are critical for cranioplasty material design and craniofacial development.
  • These biomechanical forces have not been previously quantified.

Purpose of the Study:

  • To quantify the epidural forces exerted on the cranium by brain pulsation.
  • To assess the potential impact of these forces on cranioplasty material integrity.

Main Methods:

  • Intraoperative measurement of epidural forces using a miniature force probe in 10 patients.
  • Validation of measurements by correlating force tracing with heart and ventilatory rates.

Main Results:

  • Quantified mean outward systolic normal stress (54.2 kPa) and tangential stress (345.4 kPa).

Related Experiment Videos

  • Measured systolic shear stress at 199.8 kPa.
  • Calculated cranioplasty yield stress (0.4 MPa) is within one order of magnitude of calcium-phosphate cement strength.

    • Conclusions:

    • Pulsatile brain forces are significant and play a role in cranial development via mechanotransduction.
    • Quantified stresses suggest a potential link to fatigue failure in calcium-phosphate cement cranioplasties.