Related Experiment Video
Updated: Aug 19, 2026

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
Published on: June 11, 2019
[The place of multispiral computed tomography in diagnostics of ischemic heart disease.]
S K Ternovoĭ1, A L Syrkin, P Sh Chomakhidze
1I. M. Sechenov Moscow Medical Academy; ul Bolshaya Pirogovskaya 2/6, 119881 Moscow, Russia.
Insights
Multispiral computed tomography (CT) effectively detects coronary artery calcification and myocardial changes. The calcium index, significantly higher in patients with ischemic heart disease, serves as a key diagnostic criterion.
Area of Science:
- Cardiology
- Radiology
- Medical Imaging
Background:
- Ischemic heart disease (IHD) diagnosis relies on various methods.
- Early detection of coronary artery calcification is crucial for risk stratification.
Purpose of the Study:
- To evaluate the diagnostic accuracy of multispiral CT (MSCT) for detecting coronary artery stenosis and myocardial structural changes.
- To assess the utility of the calcium index in diagnosing IHD.
Main Methods:
- MSCT with and without contrast, coronary angiography, stress tests, and echocardiography were employed.
- A total of 82 patients (56 with IHD, 26 without) were studied.
- Hemodynamic significance of stenoses was determined by comparison with coronary angiography.
Main Results:
- MSCT demonstrated high specificity (92%) and sensitivity (90%) for detecting significant stenoses (>50%) compared to angiography.
- MSCT showed 89% specificity and 91% sensitivity for diagnosing myocardial structural changes.
- The calcium index was significantly elevated in patients with IHD (253+/-28 U) versus those without (3+/-1.5 U).
Conclusions:
- MSCT is a valuable tool for diagnosing coronary artery stenosis and myocardial alterations in IHD patients.
- The calcium index derived from MSCT is a significant diagnostic marker for ischemic heart disease.
Abstract:
Multispiral computed tomography (CT) of the heart with detection of coronary artery calcification as well as clinical examination, stress tests, single photon emission computer tomography at rest and during stress, and/or stress echocardiography were used in the study of 56 patients with and 26 without ischemic heart disease (mean age 58+/-1 and 55+/-1.5 years, respectively). In 44 patients multispiral CT was performed with intravenous contrast injection and 27 patients were subjected to coronary angiography. Specificity, sensitivity of multispiral CT for detection of hemodynamically significant (>50%) stenoses compared with angiography and for diagnosis of structural changes of the myocardium were 92, 90%, and 89, 91%, respectively. Calcium index was significantly higher in patients with than without ischemic heart disease (253+/-28 and 3+/-1.5 U, respectively) and could be a significant diagnostic criterion of ischemic heart disease.
Related Concept Videos
Imaging Studies for Cardiovascular System V: CT
Imaging Studies for Cardiovascular System IV: CMRI
Acute Coronary Syndrome III: Diagnostic Studies
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
