[The place of multispiral computed tomography in diagnostics of ischemic heart disease.]

S K Ternovoĭ1, A L Syrkin, P Sh Chomakhidze

  • 1I. M. Sechenov Moscow Medical Academy; ul Bolshaya Pirogovskaya 2/6, 119881 Moscow, Russia.

Kardiologiia
|February 9, 2005
PubMed

Insights

Multispiral computed tomography (CT) effectively detects coronary artery calcification and myocardial changes. The calcium index, significantly higher in patients with ischemic heart disease, serves as a key diagnostic criterion.

Area of Science:

  • Cardiology
  • Radiology
  • Medical Imaging

Background:

  • Ischemic heart disease (IHD) diagnosis relies on various methods.
  • Early detection of coronary artery calcification is crucial for risk stratification.

Purpose of the Study:

  • To evaluate the diagnostic accuracy of multispiral CT (MSCT) for detecting coronary artery stenosis and myocardial structural changes.
  • To assess the utility of the calcium index in diagnosing IHD.

Main Methods:

  • MSCT with and without contrast, coronary angiography, stress tests, and echocardiography were employed.
  • A total of 82 patients (56 with IHD, 26 without) were studied.
  • Hemodynamic significance of stenoses was determined by comparison with coronary angiography.

Main Results:

  • MSCT demonstrated high specificity (92%) and sensitivity (90%) for detecting significant stenoses (>50%) compared to angiography.
  • MSCT showed 89% specificity and 91% sensitivity for diagnosing myocardial structural changes.
  • The calcium index was significantly elevated in patients with IHD (253+/-28 U) versus those without (3+/-1.5 U).

Conclusions:

  • MSCT is a valuable tool for diagnosing coronary artery stenosis and myocardial alterations in IHD patients.
  • The calcium index derived from MSCT is a significant diagnostic marker for ischemic heart disease.

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