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Published on: February 10, 2011
First confirmed case of vancomycin-resistant Enterococcus faecium meningitis in Turkey: case report and literature
1Department of Infectious Diseases and Clinical Microbiology, Akdeniz University, Medicine Faculty, Antalya, Turkey. inan@akdeniz.edu.tr
Abstract:
Vancomycin-resistant enterococci are unusual etiologic agents of bacterial meningitis and pose significant therapeutic difficulties. We report the first confirmed case of nosocomial vancomycin-resistant Enterococcus faecium meningitis in Turkey. The patient was treated with chloramphenicol and cerebrospinal fluid cultures became negative, but clinical success was not achieved. We also review the previously reported cases of vancomycin-resistant Enterococcus faecium meningitis.
Insights
Vancomycin-resistant Enterococcus meningitis is rare and difficult to treat. This case highlights challenges in managing this infection, even with chloramphenicol treatment.
Area of Science:
- Infectious Diseases
- Microbiology
- Neurology
Background:
- Vancomycin-resistant enterococci (VRE) are uncommon causes of bacterial meningitis.
- VRE meningitis presents significant therapeutic challenges due to antimicrobial resistance.
Purpose of the Study:
- To report the first confirmed case of nosocomial VRE meningitis in Turkey.
- To review previously reported cases of VRE meningitis.
Main Methods:
- Case report of a patient with VRE meningitis.
- Literature review of VRE meningitis cases.
Main Results:
- The patient, diagnosed with VRE meningitis, received chloramphenicol treatment.
- Cerebrospinal fluid cultures turned negative, but clinical success was not achieved.
Conclusions:
- VRE meningitis is a serious condition with limited treatment options.
- Further research is needed to establish effective therapeutic strategies for VRE meningitis.
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