First confirmed case of vancomycin-resistant Enterococcus faecium meningitis in Turkey: case report and literature

D Inan1, F Gunseren, D Colak

  • 1Department of Infectious Diseases and Clinical Microbiology, Akdeniz University, Medicine Faculty, Antalya, Turkey. inan@akdeniz.edu.tr

Insights

Vancomycin-resistant Enterococcus meningitis is rare and difficult to treat. This case highlights challenges in managing this infection, even with chloramphenicol treatment.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Neurology

Background:

  • Vancomycin-resistant enterococci (VRE) are uncommon causes of bacterial meningitis.
  • VRE meningitis presents significant therapeutic challenges due to antimicrobial resistance.

Purpose of the Study:

  • To report the first confirmed case of nosocomial VRE meningitis in Turkey.
  • To review previously reported cases of VRE meningitis.

Main Methods:

  • Case report of a patient with VRE meningitis.
  • Literature review of VRE meningitis cases.

Main Results:

  • The patient, diagnosed with VRE meningitis, received chloramphenicol treatment.
  • Cerebrospinal fluid cultures turned negative, but clinical success was not achieved.

Conclusions:

  • VRE meningitis is a serious condition with limited treatment options.
  • Further research is needed to establish effective therapeutic strategies for VRE meningitis.

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