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Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
Published on: March 11, 2021
Dependence of radiochromic film response kinetics on fractionated doses
I Ali1, J F Williamson, C Costescu
1Department of Radiation Oncology, Virginia Commonwealth University, P.O. Box 980058, Richmond, VA 23298, USA. iali@vcu.edu
Abstract:
Because the rate and magnitude of the post-exposure growth of the MD-55 radiochromic film (RCF) dosimeter response depends significantly on total dose, we have investigated the influence of fractionation and protracted dose delivery on optical density (OD) as a function of total dose and the exposure-to-densitometry time interval for a 633-nm scanning laser densitometer. Both measurements and models demonstrate that fractionation induces transient OD over responses, which can be as large as 20%, but rapidly dissipate within 24 h. However, the superposition model predicts 2-5% over responses that persist as long as 700 h.
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