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Updated: Aug 19, 2026

Strand-Specific Analysis of Proteins at Replicating DNA Strands by Enrichment and Sequencing of Protein-Associated Nascent DNA Method
Published on: May 2, 2025
Bias explorer: measurements of compositional bias in EMBL and GenBank sequence files
1Danish University of Pharmaceutical Sciences, Institute of Pharmacology, 2 Universitetsparken, DK-2100, Copenhagen Ø, Denmark. anfu@dfuni.dk
Abstract:
A Windows application for compositional analysis of sequenced genomes (EMBL or GenBank flat files) is available as freeware. The application allows the user to quantify word bias using Markov chain analysis and it allows the user to generate sliding window data for GC-skew, AT-skew, purine excess, keto excess and discrete word counts. The mathematical routines reside in a dynamic link library (DLL), which can be used independently by other applications. The software is available for download at http://www.dfuni.dk/~anfu/Bioinformatics/Main.htm.

