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Updated: Aug 19, 2026
Transient Expression in Nicotiana Benthamiana Leaves for Triterpene Production at a Preparative Scale
Published on: August 16, 2018
Two new triterpenes from the seeds of Trichosanthes cucumeroides
Zhimao Chao1, Yoichi Shibusawa, Akio Yanagida
1Institute of Chinese Materia Medica, China Academy of Traditional Chinese Medicine, 16 Dongzhimennei Nanxiaojie, Dongcheng, Beijing 100700, China. chaozhimao@sina.com
Abstract:
Two new triterpenes named 7-oxodihydrokarounitriol (1) and 7,11-dioxodihydrokarounidiol (2), and one known triterpene, 7-oxodihydrokarounidiol (3), were isolated from the unsaponifiable matter of the seeds of Trichosanthes cucumeroides. The structures of 1 and 2 were elucidated as (3alpha, 11beta, 13alpha, 14beta, 20alpha)-3,11,29-trihydroxy-13-methyl-26-norolean-8-ene-7-one, and (3alpha,13alpha,14beta,20alpha)-3,29-dihydroxy-13-methyl-26-norolean-8-ene-7,11-dione on the basis of extensive NMR (1H, 13C, 1H-1H COSY, DEPT, HMQC, HMBC and NOESY) and MS studies.
