Related Experiment Video
Updated: Aug 19, 2026

Isolation of Low Endotoxin Content Extracellular Vesicles Derived from Cancer Cell Lines
Published on: February 17, 2023
Emerging linezolid-resistant, vancomycin resistant Enterococcus faecium from a patient of a haematological unit in
Beata Krawczyk1, Alfred Samet, Marek Bronk
1Department of Microbiology, Gdańsk University of Technology, ul G Narutowicza 11/12, 80-952 Gdańsk, Poland.
Abstract:
The oxazolidinone antimicrobial, linezolid, has been approved for the treatment of infections caused by various gram-positive bacteria, including vancomycin-resistant enterococci (VRE). This is the first report on isolation of a linezolid resistant, vancomycin-resistant Enterococcus faecium (LRVREF) strain in Poland, from a Haematological Unit patient in the Clinical Hospital in Gdańsk. PCR-RFLP analysis of rDNA and allele-specific PCR of the domain V region of the 23S ribosomal RNA gene demonstrated the presence of the G2576U mutation previously reported to be associated with linezolid resistance. Both assays detected heterozygous in this position.
Related Concept Videos
Clinical Significance of Antibiotic Resistance
Mechanism of Antibiotic Resistance in MRSA