Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Calcinosis circumscripta in the dog: a retrospective pathological study.

A K Tafti1, P Hanna, A C Bourque

  • 1Department of Pathology, School of Veterinary Medicine, Shiraz University, P.O. Box 71345-1731, Shiraz, Iran.

Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine
|February 11, 2005
PubMed
Summary

Calcinosis circumscripta, a soft tissue mineralization, is uncommon in dogs, often affecting young, large breeds like German Shepherds. This study details 77 cases, noting common locations and microscopic findings, including a rare intestinal case.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Histological characterization of dilated cardiomyopathy in the juvenile toy Manchester terrier.

Veterinary pathology·2013
Same author

Cutaneous and tendon sheath mastocytomas with eosinophilic joint and tendon sheath effusions in a horse.

Journal of veterinary internal medicine·2010
Same author

Research in action: mammography utilization following breast cancer awareness campaigns in Lebanon 2002-05.

Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit·2009
Same author

Egg-laying-hormone immunoreactivity in the neural ganglia and ovary of Haliotis asinina Linnaeus.

Invertebrate neuroscience : IN·2005
Same author

A phase I study of oral ZD 1839 given daily in patients with solid tumors: IND.122, a study of the Investigational New Drug Program of the National Cancer Institute of Canada Clinical Trials Group.

Investigational new drugs·2005
Same author

Cow-level prevalence of paratuberculosis in culled dairy cows in Atlantic Canada and Maine.

Journal of dairy science·2004

Area of Science:

  • Veterinary Pathology
  • Canine Medicine
  • Soft Tissue Mineralization

Background:

  • Calcinosis circumscripta involves ectopic deposition of calcium salts in soft tissues.
  • It can be idiopathic, dystrophic, metastatic, or iatrogenic.
  • This study focuses on canine cases, a less common presentation.

Purpose of the Study:

  • To retrospectively analyze 77 canine cases of calcinosis circumscripta.
  • To characterize the signalment, lesion characteristics, and microscopic findings.
  • To report the first case of idiopathic intestinal calcinosis circumscripta in dogs.

Main Methods:

  • Retrospective review of 77 canine medical records and histopathology reports.
  • Analysis of signalment (age, breed), lesion location, size, and number.

Related Experiment Videos

  • Histopathological examination of tissue samples.

    • Main Results:

    • Most cases (88%) occurred in dogs under 4 years old, with German Shepherds, Rottweilers, and Labrador Retrievers being common breeds.
    • Lesions were typically solitary (82%), ranged from 2 mm to 13 cm, and most frequently occurred on hind feet (50%) and tongue (23%).
    • Histopathology revealed amorphous to granular basophilic material with or without granulomatous reaction and fibrous connective tissue; one dog had jejunal lesions.

    Conclusions:

    • Calcinosis circumscripta in dogs predominantly affects young, large breed animals.
    • Hind feet and tongue are common sites for lesions.
    • Idiopathic intestinal calcinosis circumscripta is a newly identified, rare manifestation in dogs.