Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Esophageal motor disorders.

Chandra Prakash1, Ray E Clouse

  • 1Division of Gastroenterology, Washington University School of Medicine, St. Louis, Missouri, USA.

Current Opinion in Gastroenterology
|February 11, 2005
PubMed
Summary

Motor dysfunction causes swallowing difficulties and esophageal issues. This study highlights the importance of excluding achalasia, a complex esophageal motility disorder, before considering other surgeries.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

In vitro reversible enzyme inhibition assays to predict drug-drug interactions: Current state and industry perspective from the IQ Consortium Enzyme Inhibition Working Group.

Drug metabolism and disposition: the biological fate of chemicals·2026
Same author

Naringenin-Loaded PCL Nanoparticles Attenuate Glial Activation and TNF-α Expression in Iron-Induced Post-traumatic Epilepsy.

Neurochemical research·2026
Same author

Anesthetic Management of Penetrating Tracheal Injury in a 3-Year-Old Child: A Case Report.

Annals of cardiac anaesthesia·2026
Same author

Future directions in drug-drug interaction evaluations: Industry perspective on the ICH M12 guidance.

Drug metabolism and pharmacokinetics·2026
Same author

Enhanced optical bistability in slotted photonic crystal structure for microwave frequency generation.

Scientific reports·2025
Same author

Synergistic Effects of Interlayer Anions in NiFe-LDH and Nickel Cobaltite Heterointerface for Energy-Efficient Alkaline Water Electrolysis.

ACS applied materials & interfaces·2025

Area of Science:

  • Gastroenterology and Foregut Surgery
  • Esophageal Motility Disorders

Background:

  • Motor dysfunction is a significant factor in oropharyngeal dysphagia and distal esophageal symptoms.
  • Minimally invasive surgical techniques for Zenker diverticula and achalasia are prominent in current research.
  • The varied presentations of achalasia necessitate careful diagnostic consideration.

Purpose of the Study:

  • To emphasize the diagnostic priority of excluding achalasia in patients presenting with symptoms potentially related to esophageal motor dysfunction.
  • To discuss the evolving understanding of achalasia's mimicry of other conditions.

Main Methods:

  • Literature review focusing on surgical management of Zenker diverticula and achalasia.
  • Analysis of diagnostic approaches for hypomotility disorders.
  • Review of conditions that can mimic idiopathic achalasia.

Main Results:

  • Systematic exclusion of achalasia is crucial before antireflux surgery, given its complex and often vague presentation.
  • The literature continues to reveal numerous conditions that can be mistaken for idiopathic achalasia.

Conclusions:

  • Accurate diagnosis of esophageal motor disorders, particularly achalasia, is paramount for effective patient management.
  • A thorough differential diagnosis is essential to avoid misattributing symptoms and to guide appropriate surgical or medical interventions.

Related Experiment Videos