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Nutritional supplements and alternative medicine.

Kristine J Krueger1, Craig J McClain, Stephen A McClave

  • 1Department of Internal Medicine, University of Louisville Medical Center, Kentucky 40292, USA.

Current Opinion in Gastroenterology
|February 11, 2005
PubMed
Summary

Complementary and alternative medicine (CAM) and nutritional supplements are increasingly popular. While some CAM therapies show promise for conditions like inflammatory bowel disease and liver disease, potential risks and drug interactions require physician awareness.

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Area of Science:

  • Integrative Medicine
  • Nutritional Science
  • Gastroenterology

Background:

  • Growing trend in healthcare: increased use of complementary and alternative medicine (CAM) and nutritional supplements.
  • Significant out-of-pocket spending on CAM in the US, with users believing in treatment efficacy.
  • Availability of Physician's Desk References for herbal therapies and dietary supplements.

Purpose of the Study:

  • To review the therapeutic benefits and risks of CAM and nutritional supplements.
  • To highlight emerging applications in specific gastrointestinal and liver conditions.
  • To emphasize the importance of physician awareness regarding CAM use.

Main Methods:

  • Review of current research on CAM and nutritional supplements.
  • Analysis of efficacy and safety data for various agents.

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  • Identification of key therapeutic areas and potential adverse events.

    • Main Results:

    • Probiotics show promise for inflammatory bowel disease.
    • Enteral nutrition is safe and effective for acute pancreatitis.
    • Peppermint oil is a common therapy for irritable bowel syndrome.
    • Antioxidants, S-adenosylmethionine, and betaine show potential in liver disease.
    • Significant safety concerns exist, including ephedra risks and CAM-induced liver failure.

    Conclusions:

    • Physicians must understand the potential benefits of CAM and supplements.
    • Awareness of potential risks, including toxicity and drug interactions, is crucial.
    • Informed patient care requires knowledge of both efficacy and safety profiles of CAM therapies.